The use of DNA molecules to encode computational problems. Standard operations of molecular biology can then be used to SOLve some NP-hard {search problems} in parallel using a very large number of molecules. The exponential scaling of NP-hard problems still remains, so this method will require a huge amount of DNA to SOLve large problems. [L. M. Adleman, "Molecular Computation of SOLutions to Combinatorial Problems", Science 266:1021-1024, 1994]. (1997-02-11)